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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMF1 All Species: 17.58
Human Site: T912 Identified Species: 24.17
UniProt: P82094 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.31
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P82094 NP_009045.2 1093 122842 T912 E R K K A I F T Q E T I K E K
Chimpanzee Pan troglodytes XP_526227 1093 122795 T912 E R K K A I F T Q E T I K E K
Rhesus Macaque Macaca mulatta XP_001088711 1092 122828 T911 E R K K A I F T Q E A I K E K
Dog Lupus familis XP_533766 1089 122761 F908 Q E R K K A V F T Q E A I K E
Cat Felis silvestris
Mouse Mus musculus B9EKI3 1091 121796 T910 E R K K T I F T Q E A L K E K
Rat Rattus norvegicus NP_446123 1093 121882 T912 E R K K T I F T Q E T L K E K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510334 1106 124384 E925 F A Q E M V K E K E R K P F P
Chicken Gallus gallus O42184 1433 161009 E1183 E L G R S R D E V T S H Q K L
Frog Xenopus laevis Q5PQ23 649 75475 E478 R L K G L L G E S H G I E E R
Zebra Danio Brachydanio rerio NP_001003522 1136 126986 E955 Q E A L K E K E R K S L S L S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572360 933 103794 S761 S Q A P L R S S P P L S L V D
Honey Bee Apis mellifera XP_394037 1326 150590 K1027 V K K E E F L K H E N S E L L
Nematode Worm Caenorhab. elegans P02566 1966 225108 E1546 Q K I I R R L E I E K E E L Q
Sea Urchin Strong. purpuratus XP_785821 1176 131318 L996 L S L T Q E A L E E K E R R L
Poplar Tree Populus trichocarpa XP_002303293 975 109171 A804 P I A R S N S A F E N G N L T
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q0WVL7 956 108335 Q785 N S S A V S E Q L P I A R Q N
Baker's Yeast Sacchar. cerevisiae P47166 707 81153 E536 S H E T I C S E E S Q H F D R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 98.5 93.1 N.A. 87.2 86.7 N.A. 81.2 21.7 22.6 59.7 N.A. 26.1 23.9 21 37.7
Protein Similarity: 100 99.4 99.1 96.1 N.A. 92.5 92 N.A. 88.3 39.9 37.3 74.6 N.A. 45.8 44.9 36.6 56.8
P-Site Identity: 100 100 93.3 6.6 N.A. 80 86.6 N.A. 6.6 6.6 20 0 N.A. 0 13.3 6.6 6.6
P-Site Similarity: 100 100 93.3 40 N.A. 86.6 93.3 N.A. 33.3 40 40 33.3 N.A. 13.3 33.3 33.3 20
Percent
Protein Identity: 25.8 N.A. N.A. 27.1 21.1 N.A.
Protein Similarity: 47.2 N.A. N.A. 45.4 39.4 N.A.
P-Site Identity: 6.6 N.A. N.A. 0 0 N.A.
P-Site Similarity: 20 N.A. N.A. 13.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 6 18 6 18 6 6 6 0 0 12 12 0 0 0 % A
% Cys: 0 0 0 0 0 6 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 6 0 0 0 0 0 0 6 6 % D
% Glu: 36 12 6 12 6 12 6 36 12 59 6 12 18 36 6 % E
% Phe: 6 0 0 0 0 6 30 6 6 0 0 0 6 6 0 % F
% Gly: 0 0 6 6 0 0 6 0 0 0 6 6 0 0 0 % G
% His: 0 6 0 0 0 0 0 0 6 6 0 12 0 0 0 % H
% Ile: 0 6 6 6 6 30 0 0 6 0 6 24 6 0 0 % I
% Lys: 0 12 42 36 12 0 12 6 6 6 12 6 30 12 30 % K
% Leu: 6 12 6 6 12 6 12 6 6 0 6 18 6 24 18 % L
% Met: 0 0 0 0 6 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 6 0 0 0 0 6 0 0 0 0 12 0 6 0 6 % N
% Pro: 6 0 0 6 0 0 0 0 6 12 0 0 6 0 6 % P
% Gln: 18 6 6 0 6 0 0 6 30 6 6 0 6 6 6 % Q
% Arg: 6 30 6 12 6 18 0 0 6 0 6 0 12 6 12 % R
% Ser: 12 12 6 0 12 6 18 6 6 6 12 12 6 0 6 % S
% Thr: 0 0 0 12 12 0 0 30 6 6 18 0 0 0 6 % T
% Val: 6 0 0 0 6 6 6 0 6 0 0 0 0 6 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _